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Licensing ensures that states and/or localities know where e-cigarettes are being sold and are better able to ensure the retailers selling them are following the law

Clinical studies have also confirmed that prenatal glucocorticoid (GC) exposure not only sensitizes the HPA axis response to painful stress of a heel-stick in full-term infants, but also increases the stress reactivity of 10-year-old-children to a standard psychological stress test [44, 45]

In 2010, the National Institute on Drug Abuse commissioned the manufacture of millions of experimental cigarettes with lower nicotine levels

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