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El desarrollo de la artritis reumatoide se basa en una predisposicin gentica, como los alelos HLA-DR4, que crean anticuerpos contra las protenas citrulinadas, y en factores desencadenantes ambientales, como las infecciones o el tabaquismo [8]
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All things considered, IM8s reputation skews sharply positive, though with some downsides