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community and clinical sources describe dermatological monitoring for these changes, especially with long-term use Injection site darkening localized hyperpigmentation Mood changes irritability reported by some during loading Managing nausea: community sources commonly describe beginning at 100-250 mcg, injecting before bed on an empty stomach, using anti-nausea medication (ondansetron) when needed, and escalating the dose gradually

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Preliminary evidence for the reliability and validity of an abbreviated profile of mood states

10.1123/ijsnem.11.4.451 111 OgasawaraR.SatoK.HigashidaK.NakazatoK.FujitaS