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PERK phosphorylates the eukaryotic translation initiator factor 2 (eIF2), which increase the translation of transcription factor-4 (ATF4) and subsequently upregulating the expression of C/EBP homologous protein (CHOP) and tribbles homolog 3 (TRIB3)

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5-reduced C21 steroids are substrates for human cytochrome P450c17

The results revealed that binge drinking treatment impaired conditional discrimination learning, motor learning, and recognition memory during adolescence and in the adult stage [28]