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This interaction leads to mRNA degradation or repression, forming a sophisticated regulatory network that is vital for proper cellular function and development, and is often implicated in various diseases (Figure 3) ( FIGURE 3 3.6.1 lncRNA UCA1 Research on the role of lncRNA UCA1 in cisplatin resistance in lung adenocarcinoma outlines several mechanisms through which UCA1 influences the expression of various genes, including ChaC1

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Likewise, the origin of the glutathione that accumulates in this compartment remains unclear, as does whether external factors, such as glutathione-rich diets or direct intake of this compound as an antioxidant supplement, might influence its levels in the tumour microenvironment

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