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The following diagram easily explains this phenomenon

Although the NAFLD-like phenotype was observed in mice fed with high-fat-Met and Tyr-deficient diets, Nrf2 accumulation was suppressed where nuclear transport of Nrf2 and fumarate in the liver was reduced (Sano et al., 2021)

It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood

Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, et al