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For the foundational coverage of each compound individually, see What Is AOD-9604

However, due to poor metabolic stability of angiotensin IV and many AngIV analogues, the inability of early analogues to penetrate the blood brain barrier, and the failure to identify the AT4 receptor, no pharmaceutical company has moved forward with their development

In academic and industrial research contexts, compounds such as AOD-9604 are utilised in receptor-binding assays, pathway modelling, mechanistic signalling analysis, and assay development workflows

HUBERMAN: And it's not something that I've returned to, except every once in a great while, I might do it to augment deep sleep just a little bit