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This lipotoxicity promotes inflammation, and inflammation fuels further fat accumulation and insulin resistance, increasing the progression of NAFLD to more severe conditions

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We resolved these to nine variantprotein pairs, and compared the variance explained in PCOS and in the respective protein levels (Supplementary Note and Supplementary Table 20), and for proteins linked to the signal at FTO BMI, similar to the logic of Steiger filtering 40

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