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clinical presentation of high-risk (massive) poisoning Patients develop mitochondrial dysfunction very early (usually within 30 grams) may present with mental status alteration and lactic acidosis within 12 hours of ingestion

Therapeutic potential of curcumin in a rat model of dextran sulfate sodium-induced ulcerative colitis by regulating the balance of Treg/Th17 Cells

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Side Effects and Safety Side effects Across preclinical studies and the small human trials published to date (~28 subjects across pilot studies), the reported adverse events stay limited: Mild injection-site irritation (rare) No systemic toxicity at therapeutic doses in published reports Oral administration: mild GI upset in sensitive individuals No immunosuppression, hormonal disruption, or metabolic side effects have been observed