Skin surface feels softer, smoother, and better hydrated to the touch, with blemishes becoming less prominent
Research characterizes its modulation of the nitric oxide system and promotion of angiogenesis upregulating VEGF signaling and supporting endothelial function as a unifying mechanism linking its diverse tissue-repair effects 5
Not all MTHFR sufferers need to be treated
Seek medical attention promptly if you experience symptoms that could suggest serious underlying conditions, including: Unexplained weight loss or persistent fatigue Jaundice (yellowing of skin or eyes), abdominal pain, or swelling Easy bruising or bleeding , or unusual skin rashes Night sweats , fever, or enlarged lymph nodes Reduced urine output , significant swelling in legs or ankles Persistent itching without obvious skin cause These symptoms may indicate liver disease, haematological disorders, or renal impairmentconditions that can elevate B12 and require specialist assessment