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Safety and Side Effects In published preclinical studies, BPC-157 presents a favorable safety profile

References Pollard, B., & Pomfrett, C

These may occur if: The injection was too shallow or too deep The fluid volume was too high for the site The product was too concentrated or acidic Local immune cells formed a small granuloma (harmless but annoying) Applying a warm compress can help disperse the fluid and reduce the lump

in December 2024 the FDA's Pharmacy Compounding Advisory Committee voted against adding it to the final 503A bulks list, citing nonclinical toxicity, an unresolved cardiac signal, and immunogenicity risk