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47 LabrouN

Thus, local homeostatic disorders and any pH alteration directly impair the integrity of the mucosa, which has a functional role in the internal and external adaptable slope (Borgogna et al., 2020

Indeed, there may be synergy between FGF-21 and GCG receptor agonism, due to their similar metabolic actions, particularly related to brown adipose tissue differentiation and activation [32], with FGF21 having additional actions in the liver, reducing hepatic lipogenesis and enhancing hepatic insulin sensitivity [66, 67]