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Additionally, recent studies have identified bacterial DNA in human and mouse adipose tissues 20,21

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While generally well-tolerated, some patients may experience side effects

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It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage

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Colchicine has been shown to induce reversible malabsorption of vitamin B12, apparently by altering the function of ileal mucosa

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