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Orthotopic model of lung cancer Stably transfected KP tumor cells expressing luciferase (KP-Luc) were injected into the tail vein of 6-week-old C57BL/6 mice, with each mouse receiving a 100 L PBS suspension containing 5 10 5 proliferating cells

At concentrations of 2% to 5%, topical spironolactone acts as a local anti-androgen without the systemic side effects (hyperkalemia, menstrual irregularity) associated with the oral form

Maresch CC, Stute DC, Alves MG, Oliveira PF, de Kretser DM, Linn T

Cancer stem cells usually overexpress ABC transporters, which contribute to dysregulation of the signal transduction network and play essential roles in tumor MDR 47