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Home-use devices are widely available but vary greatly in quality, and there is not yet enough strong evidence to show that they work as well as clinical devices

DATA AND SOFTWARE AVAILABILITY The RNA-Seq data obtained in this study has been uploaded to NCBI GEO datasets, under accession number GSE94395 ( The software to analyze the data is available at Supplementary Material Highlights

Health care professionals should be aware of this rare risk and consider acetaminophen, along with other drugs already known to have such an association, when assessing patients with potentially drug-induced skin reactions