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We know about the health risks of nicotine from studies in Sweden into the use of "Snus", a smokeless tobacco

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Inclusion criteria for the national program are being 5574 years of age and having a smoking history of 20 pack-years (active smoking or having quit no longer than 15 years ago) or being aged 5055 years of age and having the same smoking history criteria and an additional risk factor, such as exposure to toxic compounds, previous cancer history, or diagnosis of chronic obstructive pulmonary disease (COPD) or idiopathic pulmonary fibrosis (IPF) (82)