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Notably, the Hamilton Depression Rating Scale (HAMD-17) scores in this population correlate strongly with biomarkers of hepatic dysfunction (e.g., elevated gamma-glutamyl transferase) and neuronal injury (e.g., serum neurofilament light chain), suggesting a unique pathophysiology blending systemic and central nervous system (CNS) toxicity (Mirabdolhagh Hazaveh et al

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