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Second, instead of mediating the cutting of mRNA transcripts, ASOs can also be designed to target and hybridize with inhibitory elements in the 5 UTR region of the mRNA transcript

For example, a study published in the journal Nutrients in 2017 found that glutathione supplementation can enhance immune function and reduce the risk of infections

a , Uptake of [ 13 C 2 , 15 N]-GSH into mitochondria isolated from HEK-293T SLC25A39 knockout cells expressing a vector control, SLC25A39 cDNA, SLC25A10 (DIC, mitochondrial dicarboxylate carrier) or SLC25A11 (OGC, mitochondrial oxoglutarate carrier) cDNA at 5 s and 10 min

Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane