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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease

Persistently high readings without supplements can indicate liver, kidney, blood, or inflammatory conditions, so followup evaluation may be recommended

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It also provides comparison periods to evaluate whether the peptide is actually contributing to your results