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2019;8doi:10.12688/f1000research.17076.1 Dutta S, Sengupta P, Roychoudhury S, Chakravarthi S, Wang CW, Slama P

To list some of them, the modulation of the activity of cysteine-glutamate exchangers, glutamate transporters, or apoptotic pathway appears to be one of the most promising for the development of new drugs

Nevertheless, some clinical-pathological studies(postmortem brain tissue samples from AD patients) has revealed significant limitations in this theoretical framework ( Given these limitations, the establishment of a conceptual model capable of integrating multiple pathological processes and elucidating their spatiotemporal dynamics becomes imperative

Hamadneh L, Bahader M, Abuarqoub R, AlWahsh M, Alhusban A, Hikmat S