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10.1016/j.cmet.2017.10.007 Cell Metab

The volume of distribution may be overestimated in obese patients if based on body weight and the drug does not enter fatty tissues well, as is the case with digoxin

The intact garlic mainly contains non-volatile -glutamyl- S -alk(en)yl-L-cysteines, namely, -glutamyl- S -allyl-L-cysteine, -glutamyl- S-trans -1-propenyl-L-cysteine, and S -alk(en)yl-L-cysteine sulfoxides such as S -allyl-L-cysteine sulfoxide (alliin), S -( trans -1-propenyl)- L-cysteine sulfoxide (isoalliin), and S -methyl-L- cysteine sulfoxide (methiin) with a small amount of S -allyl cysteine (SAC) (Figure 1A) (Block, 1992)

Yang, Y., Xu, J., Zhou, J., Xue, J., Gao, J., Li, X., Sun, B., Yang, B., Liu, Z., Zhao, Z., Luo, Q., Zeng, Q., Zheng, L., & Xiong, C