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We also demonstrate the utility of HRMS discovery-based approach (sometimes referred to as pharmacometabolomics in clinical applications ( 35, 36 )) to advance a step forward towards precision and personalized medicine and uncover new metabolites markers that can be used to provide better typing of patients related to the kinetic of elimination of a drug or to identify inter-individual susceptibility to develop drug-induced liver injury, as it is the case here with APAP

The 6/3/3mg ratio refers to the amount of each peptide included in the blend

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(2021) used immunofluorescence with specific antibodies and found lactylation on pan-histone, H3K23, and H3K18 in oocytes and pre-implantation embryos