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Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury

This sensitivity is associated with upregulated ER stress markers (BIP and CHOP) and higher intracellular lipid peroxide levels, both of which contribute to ferroptosis ( in vitro recapitulated the effects of the combination therapy, leading to reduced cell proliferation, mitosis, and increased apoptosis

With certain genetic inefficiencies, glutathione production can be reduced 50% or more, and it is estimated that nearly 1 in 3 people has this genetic variant

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