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Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial

In some embodiments, after the first stage, the dispersed microparticles in the solvent immiscible fluid medium are isolated from the fluid medium by any convenient means of separation

By enhancing endogenous melatonin production, DSIP optimizes the sleep cycle without the need for supplements, making it particularly valuable in the management of insomnia and other sleep disorders