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Always, the noted effects were within the values for lower esophageal sphincter and for pyloric sphincter which were considered to be normal as determined before

A decrease in vitamin B12 and/or folate results in an increase in homocysteine level

However, if left untreated, it can progress and cause: Chronic fatigue and overall weakness Dizziness Pale or yellowish skin tone Mental health problems such as depression, mood swings, irritability, and anxiety Loss of appetite, nausea, and diarrhea, leading to weigh loss Paresthesia: numbness, tingling or burning sensation in feet, legs, and hands Vision problems Vitamin B12 is an essential nutrient, meaning everyone should get it either from food or supplements

Official prescribing information Centers for Disease Control and Prevention