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Dysfunction of tight junctions is thought to be a primary driver of inflammatory bowel disease and has even been tied to enhanced wheat gluten allergies in celiac disease

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H 2 S functions as a gasotransmitter that supports longevity through its role in mitochondrial respiration, redox signaling, and stress adaptation

fermentum 5716, a probiotic strain, is capable of ameliorating colonic inflammation in TNBS induced rat colitis which is also attributed to its ability to release glutathione in the gut [39]