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Some of the people in the study had smoked more than 15,000 packs of cigarettes in their life, but within a few years of quitting, many cells lining their airways showed no evidence of damage from tobacco. Lung biopsies were analysed from 16 different people, including people who used to smoke and people who still smoke, as well as people who have never smoked and children, looking for specific mutations that can lead to cancer

An additional source of ROS in smokers is cigarette smoke itself, which contains high levels of ROS such as superoxide anion, hydrogen peroxide, and hydroxyl radicals [108]

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