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In a hemophilia dog model, there was evidence of AAV integration four years after being treated with canine factor VIII (cFVIII) in an AAV8/9 vector, however, there was no evidence of tumor formation within these dogs that had AAV integration [151]

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The Diamine Oxidase Gene Is Associated with Hypersensitivity Response to Non-Steroidal Anti-Inflammatory Drugs. PLoS ONE, vol