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Even though all participants were submitted to genetic testing at screening, only in the genetic group were polymorphisms used to define smoking cessation drug prescription (varenicline 2 mg, bupropion 300 mg, or combination therapy with varenicline 2 mg + bupropion 150 mg

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77 (64), 2003420037 (2012) Reporting Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke Under Section 904(a)(3) of the Federal Food, Drug, and Cosmetic Act, Guidance for Industry (2012) FDA, Guidance for industry