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Samples were separated using a Raptor HILIC-Si 2.1 100 mm, 2.7 m LC column (Restek) with a constant flow rate of 400 l/min following a flow gradient starting at 5% Mobile Phase B (H 2 O + 5 mM AmFm +0.5% formic acid) then going up to 40% in 5 min, which was followed by re-equilibration at 5% B for 4 min and 30s

Mishra R, Upadhyay A (2025) An update on mammalian and non-mammalian animal models for biomarker development in neurodegenerative disorders

Dimensions: 4572 x 3052 px | 38.7 x 25.8 cm | 15.2 x 10.2 inches | 300dpi Date taken: 26 January 2021 Location: Essex, UK More information: Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement

In addition, these increases were significant when compared to the placebo group (P = 0.034, P = 0.026, and P = 0.002, respectively)