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Inflammatory processes play key roles in the pathogeneses of fatty liver diseases, and continuous inflammation promotes the progression of alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH)

Congenital GHD is present at birth (or shortly after) and is usually caused by genetic abnormalities or malformations in the hypothalamus or pituitary gland

However, the elevated mitochondrial activity required to sustain tumor growth often leads to increased production of mitochondrial reactive oxygen species (mtROS), accumulation of mitochondrial DNA mutations, and mitochondrial dysfunction

Vitamin C and vitamin E both require glutathione to return to their active forms after neutralizing free radicals