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It has been established that Injurious effects will not only cause damaging effects in smokers but also in non-smokers in different ways

Comprehensive genomic analyses have revealed a distinct tobacco-related mutational signature in liver tumors of smokers, characterized by cytosine-to-adenine base substitutions, dinucleotide alterations, and guanine adduct formation, patterns resembling those observed in lung and head-and-neck cancers [38,39,40]

Mem Inst Oswaldo Cruz 100(Suppl 1):1923

Common symptoms of peptic ulcers include: severe pain in the middle or upper stomach heartburn bloating nausea vomiting In most cases, treatment involves H2 blockers, PPIs, antibiotics, or protective medications that cover the ulcer like a bandage to prevent further damage