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Description

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Mice were maintained in a controlled environment: temperature range, 2026 C

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Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74

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Interestingly, cell adhesion to extracellular matrix also plays an important role in cellular metabolism: detachment from ECM inhibits glucose metabolism and mitochondrial respiration, leading to reduced energy synthesis within cells and increased intracellular ROS production (125)

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