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10.1073/pnas.0802076105 Proc
The most commonly reported side effects at therapeutic doses include mild nausea, particularly in the first week of a protocol, which typically resolves by day 7 to 10 without any dose adjustment
In an OIS model induced by Nras G12v overexpression in hepatocytes of immunodeficient Nod Scid Gamma (NSG) mice, senescent cells were successfully eliminated when treated with the anti-uPAR CAR-T cells