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Description

They produce enough in their digestive systems via bacterial fermentation

This receptor-level mechanism distinguishes the fragment from other growth hormone fragments and mimetics and makes it a valuable tool compound in studies of selective adipose metabolism and thermogenic physiology

The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]