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Cagrilintide monotherapy produced 10.8% mean body weight reduction at 26 weeks in the REWIND Phase 2 trial, while survodutide achieved 12.9% reduction at the highest evaluated dose (4.8mg weekly) in Phase 2 studies

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Individuals carrying the GSTP1* (Ile105Val rs1695) or GSTP1* (Ala114Val rs1138272) variants were less prone to develop COVID-19 as compared to the GSTP1 wild type genotypes