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Like semaglutide and tirzepatide, it is a glucagon-like peptide-1 (GLP-1) agonist, meaning it acts on GLP-1 receptors just like the natural GLP-1 hormone in your body

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Biomarker Effects Were Present Despite clinical failure, semaglutide showed biological activity: CSF biomarkers including pTau181, pTau217, and others demonstrated nominally significant reductions of approximately 10% in treated patients