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[16] In urgent situations like isoniazid overdose or vitamin B-dependent seizures, only the injection can rapidly achieve the high serum levels of pyridoxine needed to correct the problem

Goldstein AL, Hannappel E, Sosne G, Kleinman HK

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Standard injectable protocols use 0.25-0.5 mg daily via subcutaneous injection, with many researchers noting visible improvements within 5-10 days for minor wounds and 2-4 weeks for more significant skin injuries