glutathione transferases

glutathione transferases transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Glutathione Transferase - an overview

Name: glutathione transferases transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Glutathione Transferase - an overview
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The real-time monitoring and inhibition functions of GAS provide significant advantages for AD theranostics

Manns et al., 2012) (Table 3)

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GSH can be exhausted via inhibiting SLC7A11 by traditional drugs (e.g., sorafenib and sulfasalazine (SAS)) or novel compounds (e.g., erastin), thus inducing ferroptosis (Zhang et al., 2018), tumor protein 53 (TP53) (Jiang et al., 2015), nuclear factor E2 related factor 2 (NFE2L2/Nrf2) (Sun et al., 2016)