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Blher M, Aras M, Aronne LJ, et al

Its regular formulation consists of: Milk Thistle Phospholipid Proprietary Blend: milk thistle integrated into a phospholipid complex, which bridges silymarins lipophilia and hydrophobia to improve absorption and bioavailability4 Siliphos: a branded milk thistle phytosome, which research suggests is better at moving into cells and reaching the bloodstream5 About Siliphos in Life Extension, the phosphates are carriers of silybin, believed to be the primary compound responsible for milk thistle's biological activity, particularly with regard to liver health.6 Here, the Siliphos provides 47.52mg of additional silybin, so the key takeaway (again) is that Life Extension delivers increased bioavailability of an important active compound

Competing interests The authors declare no competing interests

Participants with normal renal function were eligible for inclusion if they were judged to be of general good health by the investigator, on the basis of a medical examination (including physical examination, medical history, vital signs and electrocardiogram [ECG]) with laboratory parameters within normal limits