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One of the new designs includes an image of anti-smoking activist Barb Tarbox, who died of lung cancer in 2003 at age 42

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By being informed and proactive, smokers can make smarter decisions for their well-being while reducing exposure to the most dangerous chemicals found in traditional cigarettes

[89] indicated that 2M was increased in COPD patients and was correlated with lower pulmonary diffusing capacity values, increased alveolar wall/septal thickening (fibrosis changes), and higher expressions of TGF-1, Smad4, and a-SMA