Red flags include vague descriptions (high-grade), lack of analytical reports, no contact information, or claims about health benefits that sound too good to be true
1 Many studies have shown that severely ill people have low glutathione levels, whether their conditions are cancer, AIDS, liver disease, or a chronic condition
These events recruit autophagy adaptors (p62, OPTN, NDP52) that bridge ubiquitinated OMM proteins (VDAC1, MARF, Mfn1/2) to LC3-labeled autophagosomes [30, 31]
Therefore, in future studies it will be exciting to identify more complex substrates of Mia40 that might interact with the reduced oxidoreductase in one of the above described processes so as to clarify the role of reduced Mia40 in the IMS