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The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4

Monitor levels every 6 months given high-risk status

The most common symptoms, which are mild and temporary, include abdominal pain, loose stools, and increased flatulence (mostly associated with oral supplementation)

This accomplishment helps DOM gain insights into its Medicaid population and better understand how therapies or procedures affect health outcomes and the cost of care