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Description

A peptide is a small chain made up of building blocks called amino acids

A selective non-competitive inhibitor of VMAT2 VMAT1 is a different isoform expressed in peripheral neuroendocrine cells (adrenal chromaffin cells, interneurons of sympathetic ganglia, and enterochromaffin cells that store serotonin in the GI tract)

While harnessing the immune system offers promise to clear senescent cells, the potential impact of off-target effects and unintended immune responses needs to be carefully evaluated to minimize potential harm to healthy tissues