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A substantial proportion of environmental contaminants, heavy metals, and metabolic by-products are lipophilic, i.e., fat-soluble

The functions and regulation of glutathione S-transferases in plants

Nat Commun 13:1692

Figure 2 2.2 Lipid metabolism and antioxidant systems regulate ferroptosis Lipid synthesis and catabolism directly or indirectly influence lipid peroxidation in ferroptosis