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By contrast, several mutations that decrease the tone of the GH/IGF-1 axis are associated with extended longevity in mice

After serum limitation-induction, positive FOXO4 and p53-pS15 immunofluorescence staining was stronger in the nucleus of keloid fibroblasts at 48 h, but in the nucleus of normal skin fibroblasts at 72 h

AB and IB did the original drafting, review and editing of the manuscript

show that DMSO prevents the phosphorylation of retinoblastoma, halting cells in the G1 phase of the cell cycle via alterations in PI3K pathway signalling, which they found regulates the early transitory states of hPSCs toward differentiation [17, 18]