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While ROS play a role in cellular signaling and homeostasis at low levels, excess ROS production and/or insufficient antioxidant scavenging leads to oxidative stress (Oswald et al., 2018

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Sens Actuat B Chem 190:673678 Sudeep PK, Joseph STS, Thomas KG (2005) Selective detection of cysteine and glutathione using gold nanorods

Additionally, wound-associated microbiota influence TLR signaling dynamics by producing metabolites and structural components that either activate or inhibit specific TLRs, shaping the local immune microenvironment [37]