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Tricarboxylic acid cycle metabolites as mediators of DNA methylation reprogramming in bovine preimplantation embryos

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This restoration of cellular energy is not a quick fix, but rather a gradual rebuilding of the body's metabolic foundation

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867(1):165967 Sferruzzi-Perri AN, Lopez-Tello J, Napso T, Yong HEJ (2020) Exploring the causes and consequences of maternal metabolic maladaptations during pregnancy: lessons from animal models