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Targeting mTOR1/2 by a mTOR Kinase Inhibitor (PP242) induces Apoptosis In AML Cells Under Conditions Mimicking Bone Marrow Microenvironment

10.1155/2019/4506303 151 SzikszE.PapD.LippaiR.BresN

2 (Nle-Tyr-Ile-His-Pro-Phe) and the endogenous LVV-hemorphin-7 3 (Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe), both with structural similarities to Ang IV at the N-terminal part of the peptides (Figure 1)