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First, it identifies common pathways shared by Chinese and Western medicineimmune inflammation, oxidative stress, metabolic disorder, hemodynamic abnormality, and autophagy imbalanceand links molecular pathways (HMGB1/NLRP3/NF-B, SIRT1/PGC-1, PTEN/PI3K/Akt, autophagy and podocyte markers) with clinical outcomes (24-h UP, Scr/BUN, SOD/MDA, nephrin/podocin), building a testable pathogenesismechanismindicatorprescription framework

Glutathionylation of p53 is also a causative factor in inhibition of oligomerization and in subsequently preventing its transcriptional activation [100]

Advanced Growth Factor Delivery Systems in Wound Management and Skin Regeneration